Refractory

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Resistant to medication

Merriam-Webster Online Dictionary
refractory (adjective)
1.
resisting control or authority - stubborn unmanageable
2.
a) resistant to treatment or cure - a refractory lesion
b) unresponsive to stimulus
c) - immune insusceptible after recovery they were refractory to infection
3.
difficult to fuse, corrode, or draw out , especially capable of enduring high temperature unruly
refractory (noun)
a refractory person or thing , especially a heat-resisting ceramic material
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